| Reaction Details |
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 | Report a problem with these data |
| Target | Dihydroorotate dehydrogenase (quinone), mitochondrial |
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| Ligand | BDBM16109 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321227 (CHEMBL881227) |
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| IC50 | 4000±n/a nM |
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| Citation |  Leban, J; Kralik, M; Mies, J; Gassen, M; Tentschert, K; Baumgartner, R SAR, species specificity, and cellular activity of cyclopentene dicarboxylic acid amides as DHODH inhibitors. Bioorg Med Chem Lett15:4854-7 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dihydroorotate dehydrogenase (quinone), mitochondrial |
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| Name: | Dihydroorotate dehydrogenase (quinone), mitochondrial |
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| Synonyms: | Dhodh | Dihydroorotate dehydrogenase | PYRD_MOUSE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42711.08 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1366444 |
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| Residue: | 395 |
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| Sequence: | MAWRQLRKRALDAAIILGGGGLLFTSYLTATGDDHFYAEYLMPALQRLLDPESAHRLAVR
VISLGLLPRATFQDSNMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKLGFGFVEVGSV
TPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSAVEHRLRARQQKQTQLTTDGLPLGIN
LGKNKTSVDAAADYVEGVRILGPLADYLVVNVSSPNTAGLRSLQGKTELRRLLSKVLQER
DALKGPQKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIITNTTVSRPVGLQGALRSET
GGLSGKPLRDLSTQTIREMYALTQGTIPIIGVGGVSSGQDALEKIQAGASLVQLYTALTF
LGPPVVARVKRELEALLKERGFNTVTDAIGVDHRR
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| BDBM16109 |
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| n/a |
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| Name | BDBM16109 |
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| Synonyms: | 2-[(4-phenylphenyl)carbamoyl]cyclopent-1-ene-1-carboxylic acid | Biphenyl-4-ylcarbamoyl Cyclopentene Analog 1 | CHEMBL348270 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17NO3 |
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| Mol. Mass. | 307.3432 |
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| SMILES | OC(=O)C1=C(CCC1)C(=O)Nc1ccc(cc1)-c1ccccc1 |t:3| |
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| Structure | 
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