| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50173862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320716 (CHEMBL881702) |
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| Ki | 7.5±n/a nM |
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| Citation |  Innocenti, A; Villar, R; Martinez-Merino, V; Gil, MJ; Scozzafava, A; Vullo, D; Supuran, CT Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides. Bioorg Med Chem Lett15:4872-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50173862 |
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| n/a |
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| Name | BDBM50173862 |
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| Synonyms: | 1,1-Dioxo-1H-1lambda*6*-benzo[b]thiophene-6-sulfonic acid amide | CHEMBL195946 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7NO4S2 |
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| Mol. Mass. | 245.275 |
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| SMILES | NS(=O)(=O)c1ccc2C=CS(=O)(=O)c2c1 |c:8| |
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| Structure | 
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