| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholine-binding protein |
|---|
| Ligand | BDBM50597661 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2223801 (CHEMBL5137314) |
|---|
| Ki | <100000±n/a nM |
|---|
| Citation |  Ho, TNT; Lee, HS; Swaminathan, S; Goodwin, L; Rai, N; Ushay, B; Lewis, RJ; Rosengren, KJ; Conibear, AC Posttranslational modifications of ?-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. RSC Med Chem12:1574-1584 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acetylcholine-binding protein |
|---|
| Name: | Acetylcholine-binding protein |
|---|
| Synonyms: | ACHP_LYMST | ACh-binding protein | Acetylcholine Binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 26055.52 |
|---|
| Organism: | Lymnaea stagnalis |
|---|
| Description: | Soluble acetylcholine receptor |
|---|
| Residue: | 229 |
|---|
| Sequence: | MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
|
|
|
|---|
| BDBM50597661 |
|---|
| n/a |
|---|
| Name | BDBM50597661 |
|---|
| Synonyms: | CHEMBL5180647 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C65H94N18O26S5 |
|---|
| Mol. Mass. | 1703.872 |
|---|
| SMILES | [H][C@@]12CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H]1CSSC[C@H](NC(=O)CN)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](Cc3ccc(OS(O)(=O)=O)cc3)NC(=O)[C@H](CC(O)=O)NC2=O)C(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@@]2([H])C(=O)N2CCC[C@@]2([H])C(=O)N1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
