| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2X purinoceptor 5 |
|---|
| Ligand | BDBM50540409 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2226721 (CHEMBL5140234) |
|---|
| IC50 | 8450±n/a nM |
|---|
| Citation |  Mahmood, A; Villinger, A; Iqbal, J Therapeutic potentials and structure-activity relationship of 1,3-benzodioxole N-carbamothioyl carboxamide derivatives as selective and potent antagonists of P2X4 and P2X7 receptors. Eur J Med Chem238:0 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2X purinoceptor 5 |
|---|
| Name: | P2X purinoceptor 5 |
|---|
| Synonyms: | ATP receptor | P2RX5 | P2RX5_HUMAN | P2X5 | Purinergic receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47208.74 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_612725 |
|---|
| Residue: | 422 |
|---|
| Sequence: | MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
ST
|
|
|
|---|
| BDBM50540409 |
|---|
| n/a |
|---|
| Name | BDBM50540409 |
|---|
| Synonyms: | CHEBI:34941 | CHEMBL69234 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H14N3O12PS2 |
|---|
| Mol. Mass. | 511.378 |
|---|
| SMILES | Cc1nc(\N=N\c2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
