Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50600460 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2234234 (CHEMBL5148006) |
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IC50 | 8.3±n/a nM |
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Citation | Hu, S; Ma, L; Dong, B; Shan, Q; Zhou, J; Zhang, G; Wang, M; Cen, S; Zhu, M; Wang, J; Wang, Y A kind of HIV-1 protease inhibitors containing phenols with antiviral activity against DRV-resistant variants. Bioorg Med Chem64:0 (2022) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50600460 |
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n/a |
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Name | BDBM50600460 |
Synonyms: | CHEMBL5201751 |
Type | Small organic molecule |
Emp. Form. | C30H35F3N2O7S |
Mol. Mass. | 624.668 |
SMILES | COc1cc(cc(OC)c1O)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(cc1)C(F)(F)F |r| |
Structure |
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