| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Phospholipase A2 |
|---|
| Ligand | BDBM50601469 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2237087 (CHEMBL5150983) |
|---|
| IC50 | 100±n/a nM |
|---|
| Citation |  Robello, M; Barresi, E; Baglini, E; Salerno, S; Taliani, S; Settimo, FD The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities. J Med Chem64:3508-3545 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Phospholipase A2 |
|---|
| Name: | Phospholipase A2 |
|---|
| Synonyms: | Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 16364.13 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P04054 |
|---|
| Residue: | 148 |
|---|
| Sequence: | MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
|
|
|
|---|
| BDBM50601469 |
|---|
| n/a |
|---|
| Name | BDBM50601469 |
|---|
| Synonyms: | CHEMBL5172164 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H22N2O5 |
|---|
| Mol. Mass. | 442.4633 |
|---|
| SMILES | Cc1c(Cc2ccccc2-c2ccccc2)n2cccc(OCC(O)=O)c2c1C(=O)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
