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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase receptor TYRO3 | ||
| Ligand | BDBM50602485 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2241010 (CHEMBL5155220) | ||
| IC50 | 390±n/a nM | ||
| Citation |  Wong, SW; Vivash, L; Mudududdla, R; Nguyen, N; Hermans, SJ; Shackleford, DM; Field, J; Xue, L; Aprico, A; Hancock, NC; Haskali, M; Stashko, MA; Frye, SV; Wang, X; Binder, MD; Ackermann, U; Parker, MW; Kilpatrick, TJ; Baell, JB Development of [ Eur J Med Chem226:0 (2021) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase receptor TYRO3 | |||
| Name: | Tyrosine-protein kinase receptor TYRO3 | ||
| Synonyms: | BYK | DTK | RSE | SKY | TIF | TYRO3 | TYRO3_HUMAN | Tyrosine-protein kinase SKY | ||
| Type: | Protein | ||
| Mol. Mass.: | 96894.13 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q06418 | ||
| Residue: | 890 | ||
| Sequence: |
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| BDBM50602485 | |||
| n/a | |||
| Name | BDBM50602485 | ||
| Synonyms: | CHEMBL5171919 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H37FN6O2 | ||
| Mol. Mass. | 436.5666 | ||
| SMILES | CCCCNc1ncc(C(=O)NC2CCN(CCF)CC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:23.23,wD:26.27,(2.87,-11.2,;4.2,-10.43,;5.54,-11.2,;6.87,-10.43,;8.2,-11.2,;9.54,-10.43,;10.87,-11.2,;12.21,-10.43,;12.2,-8.88,;13.54,-8.11,;13.53,-6.57,;14.87,-8.87,;16.2,-8.1,;17.54,-8.87,;18.86,-8.1,;18.87,-6.56,;20.2,-5.79,;21.53,-6.56,;22.87,-5.79,;17.53,-5.79,;16.19,-6.56,;10.87,-8.12,;10.86,-6.58,;9.53,-5.81,;8.2,-6.58,;6.87,-5.81,;6.86,-4.27,;5.53,-3.5,;8.2,-3.5,;9.53,-4.27,;9.54,-8.89,)| | ||
| Structure | 
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