| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
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| Ligand | BDBM50049744 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_344947 |
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| Ki | >3000±n/a nM |
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| Citation |  Balasubramaniam, A; Mullins, DE; Lin, S; Zhai, W; Tao, Z; Dhawan, VC; Guzzi, M; Knittel, JJ; Slack, K; Herzog, H; Parker, EM Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32-36): development of an anorectic Y4 receptor selective agonist with picomolar affinity. J Med Chem49:2661-5 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 2 |
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| Name: | Neuropeptide Y receptor type 2 |
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| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42734.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
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| Residue: | 381 |
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| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
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| BDBM50049744 |
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| n/a |
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| Name | BDBM50049744 |
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| Synonyms: | CHEMBL438548 | NPY-analogs | [Cys-Trp-Arg-Nva-Arg-Tyr-NH2]2 |
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| Type | Small organic molecule |
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| Emp. Form. | C80H118N28O14S2 |
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| Mol. Mass. | 1760.102 |
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| SMILES | CCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CSSC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |
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| Structure | 
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