Reaction Details |
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Target | Metallo-beta-lactamase L1 type 3 |
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Ligand | BDBM50191983 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_392530 (CHEMBL864291) |
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Ki | 130±n/a nM |
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Citation | Sun, Q; Law, A; Crowder, MW; Geysen, HM Homo-cysteinyl peptide inhibitors of the L1 metallo-beta-lactamase, and SAR as determined by combinatorial library synthesis. Bioorg Med Chem Lett16:5169-75 (2006) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Metallo-beta-lactamase L1 type 3 |
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Name: | Metallo-beta-lactamase L1 type 3 |
Synonyms: | BLA1_STEMA | Beta-lactamase L1 |
Type: | PROTEIN |
Mol. Mass.: | 30803.13 |
Organism: | Stenotrophomonas maltophilia |
Description: | ChEMBL_1500319 |
Residue: | 290 |
Sequence: | MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLT
ALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRR
TGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAG
HTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCD
VLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
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BDBM50191983 |
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n/a |
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Name | BDBM50191983 |
Synonyms: | 3-((1-((R)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-4-mercapto-1-oxobutan-2-yl)carbamoyl)-5-hydroxybenzoic acid | CHEMBL215590 |
Type | Small organic molecule |
Emp. Form. | C21H23N3O6S |
Mol. Mass. | 445.489 |
SMILES | NC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc(O)cc(c1)C(O)=O |
Structure |
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