| Reaction Details |
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 | Report a problem with these data |
| Target | REST corepressor 1 |
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| Ligand | BDBM50410788 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2268622 |
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| IC50 | 10.0±n/a nM |
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| Citation |  Matsuda, S; Hattori, Y; Matsumiya, K; McQuade, P; Yamashita, T; Aida, J; Sandiego, CM; Gouasmat, A; Carroll, VM; Barret, O; Tamagnan, G; Koike, T; Kimura, H Design, Synthesis, and Evaluation of [ J Med Chem64:12680-12690 (2021) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| REST corepressor 1 |
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| Name: | REST corepressor 1 |
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| Synonyms: | KIAA0071 | Protein CoREST | RCOR | RCOR1 | RCOR1_HUMAN | REST corepressor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53329.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108118 |
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| Residue: | 485 |
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| Sequence: | MPAMVEKGPEVSGKRRGRNNAAASASAAAASAAASAACASPAATAASGAAASSASAAAAS
AAAAPNNGQNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGGGMRVGPQYQAVVPDFDP
AKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNMEQALGMLFWHKHNIEK
SLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKSIASLVKFYYSWKKTR
TKTSVMDRHARKQKREREESEDELEEANGNNPIDIEVDQNKESKKEVPPTETVPQVKKEK
HSTQAKNRAKRKPPKGMFLSQEDVEAVSANATAATTVLRQLDMELVSVKRQIQNIKQTNS
ALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQV
KNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSNQKPVKSPDNSIKMPEEEDEAPVLDVR
YASAS
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| BDBM50410788 |
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| n/a |
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| Name | BDBM50410788 |
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| Synonyms: | CHEMBL5281376 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20FN3O |
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| Mol. Mass. | 325.38 |
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| SMILES | Fc1ccc(cn1)C(=O)Nc1ccc(cc1)[C@@H]1C[C@H]1NCC1CC1 |r| |
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| Structure | 
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