| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Target of rapamycin complex 2 subunit MAPKAP1 |
|---|
| Ligand | BDBM50310989 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2271765 |
|---|
| IC50 | 10.0±n/a nM |
|---|
| Citation |  Chen, Y; Zhou, X Research progress of mTOR inhibitors. Eur J Med Chem208:0 (2020) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Target of rapamycin complex 2 subunit MAPKAP1 |
|---|
| Name: | Target of rapamycin complex 2 subunit MAPKAP1 |
|---|
| Synonyms: | MAPKAP1 | MIP1 | Mitogen-activated protein kinase 2-associated protein 1 | SAPK-interacting protein 1 | SIN1 | SIN1_HUMAN | Stress-activated map kinase-interacting protein 1 | TORC2 subunit MAPKAP1 | Target of rapamycin complex 2 subunit MAPKAP1 | mSIN1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 59129.70 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_119716 |
|---|
| Residue: | 522 |
|---|
| Sequence: | MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQGSNGE
TQGYVYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIKCKNIQWKERNSKQSAQEL
KSLFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVY
LPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEGREPKLNDNVSAYCLHIAEDDGE
VDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSKESLFVRINAAHGFSLIQVDNTKVT
MKEILLKAVKRRKGSQKVSGPQYRLEKQSEPNVAVDLDSTLESQSAWEFCLVRENSSRAD
GVFEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTTDVQLGISGDKVEIDPVTNQKAS
TKFWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKHLYFESDAATVNEIVL
KVNYILESRASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
|
|
|
|---|
| BDBM50310989 |
|---|
| n/a |
|---|
| Name | BDBM50310989 |
|---|
| Synonyms: | (5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol | CHEMBL1078983 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H31N5O4 |
|---|
| Mol. Mass. | 465.5447 |
|---|
| SMILES | COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C[C@H](C)O[C@H](C)C1)N1CCOCC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
