| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-C |
|---|
| Ligand | BDBM50459994 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2280983 |
|---|
| IC50 | 640±n/a nM |
|---|
| Citation |  Wu, D; Zhang, Z; Chen, X; Yan, Y; Liu, X Angel or Devil ? - CDK8 as the new drug target. Eur J Med Chem213:0 (2021) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-C |
|---|
| Name: | Cyclin-C |
|---|
| Synonyms: | CCNC | CCNC_HUMAN | Cyclin C | SRB11 homolog | hSRB11 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33244.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_107900 |
|---|
| Residue: | 283 |
|---|
| Sequence: | MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQ
VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRF
SYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV
NDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQ
WKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS
|
|
|
|---|
| BDBM50459994 |
|---|
| n/a |
|---|
| Name | BDBM50459994 |
|---|
| Synonyms: | CHEMBL4226806 | US11471446, Compound DBA-8 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14N4 |
|---|
| Mol. Mass. | 274.3199 |
|---|
| SMILES | N#Cc1ccc2ncnc(NCCc3ccccc3)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
