| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM50612085 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2286028 |
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| Ki | 3600000±n/a nM |
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| Citation |  Kousaxidis, A; Petrou, A; Lavrentaki, V; Fesatidou, M; Nicolaou, I; Geronikaki, A Aldose reductase and protein tyrosine phosphatase 1B inhibitors as a promising therapeutic approach for diabetes mellitus. Eur J Med Chem207:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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| BDBM50612085 |
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| n/a |
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| Name | BDBM50612085 |
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| Synonyms: | CHEMBL5269879 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H35F4N3O11P2 |
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| Mol. Mass. | 823.6177 |
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| SMILES | OC(=O)c1ccc(CCNC(=O)c2cc(NC(=O)CCc3ccc(cc3)C(F)(F)P(O)(O)=O)cc(NC(=O)CCc3ccc(cc3)C(F)(F)P(O)(O)=O)c2)cc1 |
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| Structure | 
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