| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50608624 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2294250 |
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| Ki | 13±n/a nM |
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| Citation |  Ghosh, AK; Shahabi, D; Kipfmiller, M; Ghosh, AK; Johnson, M; Wang, YF; Agniswamy, J; Amano, M; Weber, IT; Mitsuya, H Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2' amide-derivatives: Synthesis, biological evaluation and structural studies. Bioorg Med Chem Lett83:0 (2023) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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|
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| BDBM50608624 |
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| n/a |
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| Name | BDBM50608624 |
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| Synonyms: | CHEMBL5274743 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N2O9S |
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| Mol. Mass. | 576.658 |
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| SMILES | [H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(cc1)C(O)=O |r| |
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| Structure | 
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