| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50570985 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2304342 |
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| Ki | 4.3±n/a nM |
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| Citation |  Nehra, B; Rulhania, S; Jaswal, S; Kumar, B; Singh, G; Monga, V Recent advancements in the development of bioactive pyrazoline derivatives. Eur J Med Chem205:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50570985 |
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| n/a |
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| Name | BDBM50570985 |
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| Synonyms: | CHEMBL4872387 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21F2N3O4S |
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| Mol. Mass. | 473.492 |
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| SMILES | COc1ccc(OC)c(c1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1cc(F)cc(F)c1 |c:13| |
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| Structure | 
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