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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Transient receptor potential cation channel subfamily V member 1 | ||
| Ligand | BDBM50226436 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_451961 (CHEMBL901119) | ||
| IC50 | 180±n/a nM | ||
| Citation |  Quintanar-Audelo, M; Fernández-Carvajal, A; Van Den Nest, W; Carreño, C; Ferrer-Montiel, A; Albericio, F Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1. J Med Chem50:6133-43 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Transient receptor potential cation channel subfamily V member 1 | |||
| Name: | Transient receptor potential cation channel subfamily V member 1 | ||
| Synonyms: | Capsaicin receptor | OTRPC1 | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 (TRPV1) | Trpv1 | Vanilloid Receptor 1 (TRPV1, VR1) | Vanilloid VR1 | Vanilloid receptor | Vanilloid receptor 1 (VRI/TRPV1) | Vanilloid receptor type 1-like | Vanilloid receptor type 1-like (TrpV1/Vr1) | Vr1 | Vr1l | osm-9-like TRP channel 1 | ||
| Type: | Transient Receptor | ||
| Mol. Mass.: | 94956.12 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | O35433 | ||
| Residue: | 838 | ||
| Sequence: |
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| BDBM50226436 | |||
| n/a | |||
| Name | BDBM50226436 | ||
| Synonyms: | CHEMBL401228 | [L-arginyl]-[N-(2,4-dichlorophenethyl)glycyl]-N-[2-(indol-3-yl)ethyl]glycinamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H36Cl2N8O3 | ||
| Mol. Mass. | 603.543 | ||
| SMILES | N[C@@H](CCCN=C(N)N)C(=O)N(CCc1ccc(Cl)cc1Cl)CC(=O)N(CCc1c[nH]c2ccccc12)CC(N)=O |wD:1.0,(-7.03,-18.3,;-5.69,-19.07,;-5.69,-20.61,;-7.03,-21.38,;-7.03,-22.92,;-8.36,-23.69,;-8.36,-25.23,;-9.7,-26,;-7.03,-26,;-4.36,-18.31,;-4.36,-16.77,;-3.03,-19.08,;-3.03,-20.62,;-1.69,-21.39,;-1.69,-22.93,;-3.03,-23.69,;-3.03,-25.23,;-1.7,-26,;-1.69,-27.54,;-.36,-25.22,;-.36,-23.68,;.97,-22.91,;-1.69,-18.31,;-.36,-19.08,;-.36,-20.62,;.97,-18.31,;.97,-16.77,;-.36,-16,;-.36,-14.46,;.88,-13.56,;.41,-12.09,;-1.13,-12.09,;-2.16,-10.94,;-3.67,-11.27,;-4.15,-12.74,;-3.11,-13.88,;-1.61,-13.56,;2.31,-19.08,;3.64,-18.31,;4.98,-19.08,;3.64,-16.77,)| | ||
| Structure | 
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