Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Transient receptor potential cation channel subfamily V member 1 | ||
| Ligand | BDBM50226433 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_451961 (CHEMBL901119) | ||
| IC50 | 1330±n/a nM | ||
| Citation |  Quintanar-Audelo, M; Fernández-Carvajal, A; Van Den Nest, W; Carreño, C; Ferrer-Montiel, A; Albericio, F Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1. J Med Chem50:6133-43 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Transient receptor potential cation channel subfamily V member 1 | |||
| Name: | Transient receptor potential cation channel subfamily V member 1 | ||
| Synonyms: | Capsaicin receptor | OTRPC1 | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 (TRPV1) | Trpv1 | Vanilloid Receptor 1 (TRPV1, VR1) | Vanilloid VR1 | Vanilloid receptor | Vanilloid receptor 1 (VRI/TRPV1) | Vanilloid receptor type 1-like | Vanilloid receptor type 1-like (TrpV1/Vr1) | Vr1 | Vr1l | osm-9-like TRP channel 1 | ||
| Type: | Transient Receptor | ||
| Mol. Mass.: | 94956.12 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | O35433 | ||
| Residue: | 838 | ||
| Sequence: |
| ||
| BDBM50226433 | |||
| n/a | |||
| Name | BDBM50226433 | ||
| Synonyms: | CHEMBL395124 | [L-arginyl]-[N-[2-(indol-3-yl)-ethyl]glycyl]-N-[(2-(indol-3-yl)ethyl)]glycinamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H39N9O3 | ||
| Mol. Mass. | 573.6892 | ||
| SMILES | N[C@@H](CCCN=C(N)N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)N(CCc1c[nH]c2ccccc12)CC(N)=O |wD:1.0,(12.78,-1.15,;14.12,-1.92,;14.12,-3.46,;12.78,-4.23,;12.78,-5.77,;11.45,-6.54,;11.45,-8.08,;10.11,-8.85,;12.78,-8.85,;15.45,-1.15,;15.45,.39,;16.78,-1.92,;16.78,-3.46,;18.12,-4.23,;18.12,-5.77,;16.87,-6.68,;17.35,-8.14,;18.89,-8.14,;19.91,-9.28,;21.42,-8.96,;21.89,-7.49,;20.86,-6.36,;19.37,-6.68,;18.12,-1.15,;19.45,-1.92,;19.45,-3.46,;20.78,-1.15,;20.78,.39,;19.45,1.16,;19.45,2.7,;20.69,3.6,;20.22,5.06,;18.68,5.07,;17.65,6.21,;16.14,5.89,;15.66,4.41,;16.7,3.28,;18.2,3.6,;22.12,-1.92,;23.45,-1.15,;24.79,-1.92,;23.45,.39,)| | ||
| Structure | 
| ||