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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Transient receptor potential cation channel subfamily V member 1 | ||
| Ligand | BDBM50226430 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_451961 (CHEMBL901119) | ||
| IC50 | 520±n/a nM | ||
| Citation |  Quintanar-Audelo, M; Fernández-Carvajal, A; Van Den Nest, W; Carreño, C; Ferrer-Montiel, A; Albericio, F Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1. J Med Chem50:6133-43 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Transient receptor potential cation channel subfamily V member 1 | |||
| Name: | Transient receptor potential cation channel subfamily V member 1 | ||
| Synonyms: | Capsaicin receptor | OTRPC1 | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 (TRPV1) | Trpv1 | Vanilloid Receptor 1 (TRPV1, VR1) | Vanilloid VR1 | Vanilloid receptor | Vanilloid receptor 1 (VRI/TRPV1) | Vanilloid receptor type 1-like | Vanilloid receptor type 1-like (TrpV1/Vr1) | Vr1 | Vr1l | osm-9-like TRP channel 1 | ||
| Type: | Transient Receptor | ||
| Mol. Mass.: | 94956.12 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | O35433 | ||
| Residue: | 838 | ||
| Sequence: |
| ||
| BDBM50226430 | |||
| n/a | |||
| Name | BDBM50226430 | ||
| Synonyms: | CHEMBL400008 | [L-arginyl]-[N-[2-(indol-3-yl)ethyl]glycyl]-N-(2,4-dichlorophenethyl)glycinamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H36Cl2N8O3 | ||
| Mol. Mass. | 603.543 | ||
| SMILES | N[C@@H](CCCN=C(N)N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)N(CCc1ccc(Cl)cc1Cl)CC(N)=O |wD:1.0,(27.93,-2.09,;29.26,-2.86,;29.26,-4.4,;27.92,-5.17,;27.92,-6.71,;26.59,-7.48,;26.59,-9.02,;25.26,-9.79,;27.92,-9.79,;30.59,-2.09,;30.59,-.55,;31.93,-2.86,;31.93,-4.4,;33.26,-5.17,;33.26,-6.71,;32.02,-7.62,;32.49,-9.08,;34.03,-9.08,;35.06,-10.22,;36.56,-9.9,;37.04,-8.43,;36.01,-7.3,;34.51,-7.62,;33.26,-2.09,;34.59,-2.86,;34.59,-4.4,;35.93,-2.09,;35.93,-.55,;34.59,.22,;34.6,1.76,;33.26,2.53,;33.26,4.08,;34.59,4.85,;34.59,6.39,;35.93,4.08,;35.93,2.53,;37.27,1.76,;37.26,-2.86,;38.6,-2.09,;39.93,-2.86,;38.6,-.55,)| | ||
| Structure | 
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