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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Transient receptor potential cation channel subfamily V member 1 | ||
| Ligand | BDBM50226434 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_451961 (CHEMBL901119) | ||
| IC50 | 1100±n/a nM | ||
| Citation |  Quintanar-Audelo, M; Fernández-Carvajal, A; Van Den Nest, W; Carreño, C; Ferrer-Montiel, A; Albericio, F Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1. J Med Chem50:6133-43 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Transient receptor potential cation channel subfamily V member 1 | |||
| Name: | Transient receptor potential cation channel subfamily V member 1 | ||
| Synonyms: | Capsaicin receptor | OTRPC1 | TRPV1_RAT | Transient receptor potential cation channel subfamily V member 1 (TRPV1) | Trpv1 | Vanilloid Receptor 1 (TRPV1, VR1) | Vanilloid VR1 | Vanilloid receptor | Vanilloid receptor 1 (VRI/TRPV1) | Vanilloid receptor type 1-like | Vanilloid receptor type 1-like (TrpV1/Vr1) | Vr1 | Vr1l | osm-9-like TRP channel 1 | ||
| Type: | Transient Receptor | ||
| Mol. Mass.: | 94956.12 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | O35433 | ||
| Residue: | 838 | ||
| Sequence: |
| ||
| BDBM50226434 | |||
| n/a | |||
| Name | BDBM50226434 | ||
| Synonyms: | CHEMBL392540 | [L-arginyl]-N-[2-(indol-3-yl)ethyl]glycine 2-(indol-3-yl)ethylamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H36N8O2 | ||
| Mol. Mass. | 516.6378 | ||
| SMILES | N[C@@H](CCCN=C(N)N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCCc1c[nH]c2ccccc12 |wD:1.0,(8.54,-38.39,;9.88,-39.16,;9.88,-40.7,;8.54,-41.47,;8.54,-43.01,;7.21,-43.78,;7.21,-45.32,;5.87,-46.09,;8.54,-46.09,;11.21,-38.39,;11.21,-36.85,;12.54,-39.16,;12.54,-40.7,;13.88,-41.47,;13.88,-43.01,;12.64,-43.92,;13.11,-45.38,;14.65,-45.38,;15.68,-46.52,;17.18,-46.2,;17.65,-44.73,;16.62,-43.6,;15.13,-43.92,;13.88,-38.39,;15.21,-39.16,;15.21,-40.7,;16.55,-38.39,;16.55,-36.85,;15.21,-36.08,;15.21,-34.54,;16.45,-33.64,;15.98,-32.18,;14.44,-32.17,;13.41,-31.03,;11.9,-31.35,;11.42,-32.83,;12.46,-33.96,;13.96,-33.64,)| | ||
| Structure | 
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