| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50228648 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_461685 (CHEMBL927706) |
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| Ki | >10000±n/a nM |
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| Citation |  Seong, CM; Park, WK; Park, CM; Kong, JY; Park, NS Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett18:738-43 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50228648 |
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| n/a |
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| Name | BDBM50228648 |
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| Synonyms: | 5,7-dichloro-3-(3-hydroxyphenyl)-3-methylquinoline-2,4(1H,3H)-dione | CHEMBL404352 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11Cl2NO3 |
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| Mol. Mass. | 336.169 |
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| SMILES | CC1(C(=O)Nc2cc(Cl)cc(Cl)c2C1=O)c1cccc(O)c1 |w:1.0| |
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| Structure | 
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