| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50250840 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_486952 (CHEMBL1012214) |
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| Ki | 2000±n/a nM |
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| Citation |  Hu, JF; Schetz, JA; Kelly, M; Peng, JN; Ang, KK; Flotow, H; Leong, CY; Ng, SB; Buss, AD; Wilkins, SP; Hamann, MT New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea. J Nat Prod65:476-80 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | undefined |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28223 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM50250840 |
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| n/a |
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| Name | BDBM50250840 |
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| Synonyms: | 5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dimethyl-imidazolidin-4-one | 6-bromoaplysinopsin | CHEMBL463249 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13BrN4O |
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| Mol. Mass. | 333.183 |
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| SMILES | CN1C(=N)N(C)\C(=C\c2c[nH]c3cc(Br)ccc23)C1=O |
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| Structure | 
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