Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50250840 (5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dim...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50250841 (CHEMBL463250 | N-3'-ethylaplysinopsin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50250840 (5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50250839 (6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50250841 (CHEMBL463250 | N-3'-ethylaplysinopsin) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50250839 (6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopy | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM8726 (5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular and Cell Biology Curated by ChEMBL | Assay Description inhibition of Mycobacterium tuberculosis InhA after 20 mins by fluorometric assay | J Nat Prod 65: 1037-8 (2002) BindingDB Entry DOI: 10.7270/Q22N521Z | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM50250839 (6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assay | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasmepsin II (Plasmodium falciparum) | BDBM50250839 (6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Mississippi Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum plasmepsin-2 by fluorescence polarization assay | J Nat Prod 65: 476-80 (2002) BindingDB Entry DOI: 10.7270/Q2QC0379 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50242321 (Agonodepside A | CHEMBL454588) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Molecular and Cell Biology Curated by ChEMBL | Assay Description inhibition of Mycobacterium tuberculosis InhA after 20 mins by fluorometric assay | J Nat Prod 65: 1037-8 (2002) BindingDB Entry DOI: 10.7270/Q22N521Z | |||||||||||
More data for this Ligand-Target Pair |