| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
|---|
| Ligand | BDBM24631 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_553548 (CHEMBL958731) |
|---|
| IC50 | 9100±n/a nM |
|---|
| Citation |  Congreve, M; Chessari, G; Tisi, D; Woodhead, AJ Recent developments in fragment-based drug discovery. J Med Chem51:3661-80 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase 2 |
|---|
| Name: | Cyclin-dependent kinase 2 |
|---|
| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
|---|
| Type: | Enzyme Subunit |
|---|
| Mol. Mass.: | 33938.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P24941 |
|---|
| Residue: | 298 |
|---|
| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
|
|
|
|---|
| BDBM24631 |
|---|
| n/a |
|---|
| Name | BDBM24631 |
|---|
| Synonyms: | 4-[(6-chloropyrazin-2-yl)amino]benzene-1-sulfonamide | 4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide, 10 | CHEMBL487738 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H9ClN4O2S |
|---|
| Mol. Mass. | 284.722 |
|---|
| SMILES | NS(=O)(=O)c1ccc(Nc2cncc(Cl)n2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
