| Reaction Details |
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 | Report a problem with these data |
| Target | Bombesin receptor subtype-3 |
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| Ligand | BDBM50275901 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_496868 (CHEMBL998537) |
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| EC50 | >32000±n/a nM |
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| Citation |  Carlton, DL; Collin-Smith, LJ; Daniels, AJ; Deaton, DN; Goetz, AS; Laudeman, CP; Littleton, TR; Musso, DL; Morgan, RJ; Szewczyk, JR; Zhang, C Discovery of small molecule agonists for the bombesin receptor subtype 3 (BRS-3) based on an omeprazole lead. Bioorg Med Chem Lett18:5451-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bombesin receptor subtype-3 |
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| Name: | Bombesin receptor subtype-3 |
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| Synonyms: | BRS-3 | BRS3 | BRS3_HUMAN | Bombesin 3 | Bombesin like receptor 3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44424.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Bombesin 3 BRS3 HUMAN::P32247 |
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| Residue: | 399 |
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| Sequence: | MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISV
GILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGC
KVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFAL
PEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLI
ARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQT
YVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADT
SLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
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| BDBM50275901 |
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| n/a |
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| Name | BDBM50275901 |
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| Synonyms: | 2-((6-chlorobenzo[d][1,3]dioxol-5-yloxy)methyl)-6-phenoxy-1H-benzo[d]imidazole | CHEMBL469758 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15ClN2O4 |
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| Mol. Mass. | 394.808 |
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| SMILES | Clc1cc2OCOc2cc1OCc1nc2ccc(Oc3ccccc3)cc2[nH]1 |
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| Structure | 
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