| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50282136 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210120 |
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| IC50 | 1500±n/a nM |
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| Citation |  Yokota, M; Imamaki, K; Uchibori, S; Kondo, M; Kosakai, K; Tomiyama, T Role of sulfonamide moiety in non-prostanoid txa2 receptor antagonist kt2-962 : modifications of this moiety and the resulting activities Bioorg Med Chem Lett3:1687-1692 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36943.05 |
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| Organism: | RAT |
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| Description: | Thromboxane A2 TBXA2R RAT::P34978 |
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| Residue: | 341 |
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| Sequence: | MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRS
SFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLL
LGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSW
CFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEM
MVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQIL
DPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
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| BDBM50282136 |
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| n/a |
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| Name | BDBM50282136 |
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| Synonyms: | 6-Isopropyl-3-(5-phenylsulfamoyl-pentyl)-azulene-1-carboxylic acid | CHEMBL297275 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29NO4S |
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| Mol. Mass. | 439.567 |
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| SMILES | CC(C)c1ccc2c(CCCCCS(=O)(=O)Nc3ccccc3)cc(C(O)=O)c2cc1 |
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| Structure | 
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