Reaction Details |
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Target | Thromboxane A2 receptor |
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Ligand | BDBM50002765 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_210120 |
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IC50 | 1500±n/a nM |
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Citation | Yokota, M; Imamaki, K; Uchibori, S; Kondo, M; Kosakai, K; Tomiyama, T Role of sulfonamide moiety in non-prostanoid txa2 receptor antagonist kt2-962 : modifications of this moiety and the resulting activities Bioorg Med Chem Lett3:1687-1692 (1993) Article |
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More Info.: | Get all data from this article, Assay Method |
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Thromboxane A2 receptor |
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Name: | Thromboxane A2 receptor |
Synonyms: | TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36943.05 |
Organism: | RAT |
Description: | Thromboxane A2 TBXA2R RAT::P34978 |
Residue: | 341 |
Sequence: | MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRS
SFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLL
LGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSW
CFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEM
MVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQIL
DPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
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BDBM50002765 |
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n/a |
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Name | BDBM50002765 |
Synonyms: | BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid (BM 13177) | [4-(2-Benzenesulfonylamino-ethyl)-phenoxy]-acetic acid(sulotroban) |
Type | Small organic molecule |
Emp. Form. | C16H17NO5S |
Mol. Mass. | 335.375 |
SMILES | OC(=O)COc1ccc(CCNS(=O)(=O)c2ccccc2)cc1 |
Structure |
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