| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50285020 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_40038 |
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| IC50 | 250±n/a nM |
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| Citation |  Lowe, JA; Drozda, SE; McLean, S; Bryce, DK; Crawford, RT; Zorn, S; Morrone, J; Appleton, TA; Lombardo, F A water soluble benzazepine cholecystokinin-B receptor antagonist Bioorg Med Chem Lett5:1933-1936 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor |
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| Type: | n/a |
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| Mol. Mass.: | 48229.77 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 430 |
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| Sequence: | MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRS
SSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLL
SYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSY
SHMSTSAPPP
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| BDBM50285020 |
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| n/a |
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| Name | BDBM50285020 |
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| Synonyms: | CHEMBL292856 | N-tert-Butyl-2-((3R,5R)-5-isopropyl-8-methyl-2-oxo-3-{3-[3-(1H-tetrazol-5-yl)-phenyl]-ureido}-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N8O3 |
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| Mol. Mass. | 532.6372 |
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| SMILES | CC(C)[C@H]1C[C@@H](NC(=O)Nc2cccc(c2)-c2nnn[nH]2)C(=O)N(CC(=O)NC(C)(C)C)c2cc(C)ccc12 |
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| Structure | 
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