| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
|---|
| Ligand | BDBM50285358 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_34652 |
|---|
| IC50 | 38±n/a nM |
|---|
| Citation |  Fitch, KJ; Walsh, TF; Patchett, AA; Chang, RS; Siegl, PK; Faust, KA; Chen, TB; Lotti, VJ; Kivlighn, SD; Zingaro, GJ; Greenlee, WJ AT1 selective angiotensin II antagonists with phenoxyphenylacetic acid as a biphenyl replacement part I Bioorg Med Chem Lett5:155-158 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Type-1 angiotensin II receptor |
|---|
| Name: | Type-1 angiotensin II receptor |
|---|
| Synonyms: | AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41009.15 |
|---|
| Organism: | RABBIT |
|---|
| Description: | ANGIOTENSIN AT1 AGTR1 RABBIT::P34976 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
|
|
|
|---|
| BDBM50285358 |
|---|
| n/a |
|---|
| Name | BDBM50285358 |
|---|
| Synonyms: | (2-Methoxy-phenyl)-[4-(7-methyl-2-propyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-acetic acid | CHEMBL289640 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H27N3O4 |
|---|
| Mol. Mass. | 445.5103 |
|---|
| SMILES | CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2OC)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
