| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
|---|
| Ligand | BDBM50285820 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_35407 |
|---|
| IC50 | 150±n/a nM |
|---|
| Citation |  Mederski, WW; Dorsch, D; Osswald, M; Beier, N; Lues, I; Minck, KO; Schelling, P; Ladstetter, BJ 4,5-Dihydro-4-oxo-3H-imidazo[4,5-c]pyridines: potent arylacetic acid-derived AT1 antagonists with improved affinity for the AT2 receptor Bioorg Med Chem Lett5:2665-2670 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Type-2 angiotensin II receptor |
|---|
| Name: | Type-2 angiotensin II receptor |
|---|
| Synonyms: | AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41346.62 |
|---|
| Organism: | RAT |
|---|
| Description: | Angiotensin II AT2 0 0::P35351 |
|---|
| Residue: | 363 |
|---|
| Sequence: | MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFA
VNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDT
FVS
|
|
|
|---|
| BDBM50285820 |
|---|
| n/a |
|---|
| Name | BDBM50285820 |
|---|
| Synonyms: | CHEMBL88663 | {2-Ethyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-imidazo[4,5-c]pyridin-5-yl}-phenyl-acetic acid isopropyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H31N7O3 |
|---|
| Mol. Mass. | 573.6443 |
|---|
| SMILES | CCc1nc2ccn(C(C(=O)OC(C)C)c3ccccc3)c(=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
