| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50286176 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49403 |
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| IC50 | 1400±n/a nM |
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| Citation |  Holladay, MW; Bennett, MJ; Bai, H; Ralston, JW; Kerwin, JF; Stashko, M; Miller, TR; O'Neill, AB; Nadzan, AM; Brioni, J; Lin, CW Amino acid-derived piperidides as novel CCKB ligands with anxiolytic-like properties Bioorg Med Chem Lett5:3057-3062 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor |
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| Type: | n/a |
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| Mol. Mass.: | 48229.77 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 430 |
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| Sequence: | MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRS
SSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLL
SYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSY
SHMSTSAPPP
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| BDBM50286176 |
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| n/a |
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| Name | BDBM50286176 |
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| Synonyms: | 1-[2-((R)-4-Benzoyl-piperidin-1-yl)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-3-m-tolyl-urea | CHEMBL323127 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H32N4O3 |
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| Mol. Mass. | 508.6108 |
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| SMILES | Cc1cccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N2CCC(CC2)C(=O)c2ccccc2)c1 |
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| Structure | 
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