| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM50286817 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_195958 |
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| IC50 | 3000±n/a nM |
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| Citation |  Dee, MF; Rosati, RL Synthesis of α-hydroxy statine through a facially selective osmylation of a chiral α-amido crotonate Bioorg Med Chem Lett5:949-952 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | Angiotensinogenase | REN | RENI_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 45058.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 406 |
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| Sequence: | MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEW
SQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRL
YTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEM
PALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGG
QIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISG
STSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK
LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
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| BDBM50286817 |
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| n/a |
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| Name | BDBM50286817 |
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| Synonyms: | 4-{(2S,3R,4S)-4-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-2,3-dihydroxy-6-methyl-heptanoylamino}-butyric acid | CHEMBL172585 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H48N6O9 |
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| Mol. Mass. | 660.7583 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](O)[C@H](O)C(=O)NCCCC(O)=O |
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| Structure | 
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