| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50287271 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_48255 |
|---|
| IC50 | >1000±n/a nM |
|---|
| Citation |  Kawanishi, Y; Ishihara, S; Tsushima, T; Seno, K; Miyagoshi, M; Hagishita, S; Ishikawa, M; Shima, N; Shimamura, M; Ishihara, Y Synthesis and pharmacological evaluation of highly potent dual histamine H2 and gastrin receptor antagonists Bioorg Med Chem Lett6:1427-1430 (1996) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49196.59 |
|---|
| Organism: | MOUSE |
|---|
| Description: | Cholecystokinin A CCKBR MOUSE::P56481 |
|---|
| Residue: | 453 |
|---|
| Sequence: | MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGL
ISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCY
VQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANT
WRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPR
ARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50287271 |
|---|
| n/a |
|---|
| Name | BDBM50287271 |
|---|
| Synonyms: | (3-{2-[2-(2,2-Diamino-vinyl)-thiazol-4-ylmethylsulfanyl]-ethylcarbamoyl}-propyl)-carbamic acid 3-[(R)-1-methyl-2-oxo-3-(3-m-tolyl-ureido)-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl]-phenyl ester | CHEMBL286835 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C37H41N9O5S2 |
|---|
| Mol. Mass. | 755.909 |
|---|
| SMILES | CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)c1cccc(OC(=O)NCCCC(=O)NCCSCc2csc(CC(N)=N)n2)c1 |c:9| |
|---|
| Structure | 
|
|---|
Search and Browse
