| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50228840 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_225796 |
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| IC50 | 2.3±n/a nM |
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| Citation |  Tamura, SY; Shamblin, BM; Brunck, TK; Ripka, WC RATIONAL DESIGN, SYNTHESIS, AND SERINE PROTEASE INHIBITORY ACTIVITY OF NOVEL P1-ARGININOYL HETEROCYCLES Bioorg Med Chem Lett7:1359-1364 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50228840 |
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| n/a |
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| Name | BDBM50228840 |
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| Synonyms: | (S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-(benzooxazole-2-carbonyl)-4-guanidino-butyl]-amide; TFA | CHEMBL436851 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H43N7O5 |
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| Mol. Mass. | 617.7384 |
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| SMILES | [#6]C([#6])([#6])[#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-c1nc2ccccc2o1 |
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| Structure | 
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