| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50008634 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49402 |
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| IC50 | 190±n/a nM |
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| Citation |  Armour, DR; Aston, NM; Morriss, KM; Congreve, MS; Hawcock, AB; Marquess, D; Mordaunt, JE; Richards, SA; Ward, P 1,4-Benzodiazepin-2-one derived neurokinin-1 receptor antagonists Bioorg Med Chem Lett7:2037-2042 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_HUMAN | CCKRA | Cholecystokinin receptor | Cholecystokinin receptor type A | Cholecystokinin-1 Receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 47859.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Stable expression of human CCK-1 receptors in HEK 293 cells. |
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| Residue: | 428 |
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| Sequence: | MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNT
LVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYF
MGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYS
NLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGI
KFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNS
SAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSY
TSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSH
MSASVPPQ
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| BDBM50008634 |
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| n/a |
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| Name | BDBM50008634 |
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| Synonyms: | (S)-3,4-Dichloro-N-[1-dipentylcarbamoyl-2-(1H-indol-3-yl)-ethyl]-benzamide | CHEMBL267339 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H35Cl2N3O2 |
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| Mol. Mass. | 516.502 |
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| SMILES | CCCCCN(CCCCC)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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