| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Genome polyprotein |
|---|
| Ligand | BDBM50289951 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_158973 |
|---|
| IC50 | 1300±n/a nM |
|---|
| Citation |  Abood, NA; Schretzman, LA; Flynn, DL; Houseman, KA; Wittwer, AJ; Dilworth, VM; Hippenmeyer, PJ; Holwerda, BC Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture Bioorg Med Chem Lett7:2105-2108 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Genome polyprotein |
|---|
| Name: | Genome polyprotein |
|---|
| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44361.04 |
|---|
| Organism: | Human rhinovirus B |
|---|
| Description: | ChEMBL_158953 |
|---|
| Residue: | 401 |
|---|
| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
|
|
|
|---|
| BDBM50289951 |
|---|
| n/a |
|---|
| Name | BDBM50289951 |
|---|
| Synonyms: | CHEMBL63952 | [5-Methyl-4-oxo-2-(1-phenyl-ethylamino)-4H-benzo[d][1,3]oxazin-6-yl]-carbamic acid tert-butyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H25N3O4 |
|---|
| Mol. Mass. | 395.4516 |
|---|
| SMILES | C[C@@H](Nc1nc2ccc(NC(=O)OC(C)(C)C)c(C)c2c(=O)o1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
