| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsinogen B |
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| Ligand | BDBM50289952 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_49455 (CHEMBL656928) |
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| IC50 | 65±n/a nM |
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| Citation |  Abood, NA; Schretzman, LA; Flynn, DL; Houseman, KA; Wittwer, AJ; Dilworth, VM; Hippenmeyer, PJ; Holwerda, BC Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture Bioorg Med Chem Lett7:2105-2108 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsinogen B |
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| Name: | Chymotrypsinogen B |
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| Synonyms: | Beta-chymotrypsin | CTRB | CTRB1 | CTRB1_HUMAN | Chymotrypsin B chain A | Chymotrypsin B chain B | Chymotrypsin B chain C | Chymotrypsinogen B | Synonyms=CTRB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27713.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_10909 |
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| Residue: | 263 |
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| Sequence: | MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC
GGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNND
ITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPL
LSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCST
SSPGVYARVTKLIPWVQKILAAN
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| BDBM50289952 |
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| n/a |
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| Name | BDBM50289952 |
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| Synonyms: | 6-Dimethylamino-5-methyl-2-(1-phenyl-ethylamino)-benzo[d][1,3]oxazin-4-one | CHEMBL294771 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21N3O2 |
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| Mol. Mass. | 323.3889 |
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| SMILES | C[C@@H](Nc1nc2ccc(N(C)C)c(C)c2c(=O)o1)c1ccccc1 |
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| Structure | 
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