| Reaction Details |
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 | Report a problem with these data |
| Target | Polyamine oxidase 1 |
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| Ligand | BDBM50294097 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_570655 (CHEMBL1033595) |
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| pH | 6.5±n/a |
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| Ki | 1720±n/a nM |
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| Comments | extracted |
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| Citation |  Manetti, F; Cona, A; Angeli, L; Mugnaini, C; Raffi, F; Capone, C; Dreassi, E; Zizzari, AT; Tisi, A; Federico, R; Botta, M Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase. J Med Chem52:4774-85 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyamine oxidase 1 |
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| Name: | Polyamine oxidase 1 |
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| Synonyms: | MPAO | MPAO1 | PAO | PAO1_MAIZE | Polyamine oxidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56339.65 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_570655 |
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| Residue: | 500 |
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| Sequence: | MSSSPSFGLLAVAALLLALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLL
ILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYL
AQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPN
GPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYL
AGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQ
SDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVW
QEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPR
WWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAE
ILINCAQKKMCKYHVQGKYD
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| BDBM50294097 |
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| n/a |
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| Name | BDBM50294097 |
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| Synonyms: | CHEMBL550629 | N1-(5-Aminopentyl)-N3-(cyclohexylethyl)guanidine bis(trifluoroacetate) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H30N4 |
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| Mol. Mass. | 254.4148 |
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| SMILES | NCCCCCN=C(N)NCCC1CCCCC1 |w:6.5| |
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| Structure | 
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