| Reaction Details |
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 | Report a problem with these data |
| Target | Polyamine oxidase 1 |
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| Ligand | BDBM50294110 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_570655 (CHEMBL1033595) |
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| pH | 6.5±n/a |
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| Ki | 1.7±n/a nM |
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| Comments | extracted |
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| Citation |  Manetti, F; Cona, A; Angeli, L; Mugnaini, C; Raffi, F; Capone, C; Dreassi, E; Zizzari, AT; Tisi, A; Federico, R; Botta, M Synthesis and biological evaluation of guanidino compounds endowed with subnanomolar affinity as competitive inhibitors of maize polyamine oxidase. J Med Chem52:4774-85 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyamine oxidase 1 |
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| Name: | Polyamine oxidase 1 |
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| Synonyms: | MPAO | MPAO1 | PAO | PAO1_MAIZE | Polyamine oxidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56339.65 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_570655 |
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| Residue: | 500 |
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| Sequence: | MSSSPSFGLLAVAALLLALSLAQHGSLAATVGPRVIVVGAGMSGISAAKRLSEAGITDLL
ILEATDHIGGRMHKTNFAGINVELGANWVEGVNGGKMNPIWPIVNSTLKLRNFRSDFDYL
AQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKLSATLHASGRDDMSILAMQRLNEHQPN
GPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPLATFSDFGDDVYFVADQRGYEAVVYYL
AGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQ
SDLIQFKPKLPTWKVRAIYQFDMAVYTKIFLKFPRKFWPEGKGREFFLYASSRRGYYGVW
QEFEKQYPDANVLLVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPR
WWSDRFYKGTFSNWPVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAE
ILINCAQKKMCKYHVQGKYD
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| BDBM50294110 |
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| n/a |
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| Name | BDBM50294110 |
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| Synonyms: | 1,1'-(8,8'-azanediylbis(octane-8,1-diyl))bis(3-(3-methylbut-2-enyl)guanidine) | 1,17-Bis(N1-gamma.gamma-dimethylallyl)guanidino-9-azaheptadecano tris(trifluoroacetate) | CHEMBL560899 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H57N7 |
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| Mol. Mass. | 491.7991 |
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| SMILES | [#6]\[#6](-[#6])=[#6]\[#6]-[#7]-[#6](-[#7])=[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](-[#7])=[#7]-[#6]\[#6]=[#6](\[#6])-[#6] |w:29.29,8.8| |
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| Structure | 
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