| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2D6 |
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| Ligand | BDBM50295255 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_577702 (CHEMBL1063962) |
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| IC50 | 32000±n/a nM |
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| Citation |  Gudmundsson, KS; Boggs, SD; Sebahar, PR; Richardson, LD; Spaltenstein, A; Golden, P; Sethna, PB; Brown, KW; Moniri, K; Harvey, R; Romines, KR Tetrahydrocarbazole amides with potent activity against human papillomaviruses. Bioorg Med Chem Lett19:4110-4 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2D6 |
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| Name: | Cytochrome P450 2D6 |
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| Synonyms: | CP2D6_HUMAN | CYP2D6 | CYP2DL1 | CYPIID6 | Cytochrome P450 2D6 (CYP2D6) | Debrisoquine 4-hydroxylase | P450-DB1 |
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| Type: | Protein |
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| Mol. Mass.: | 55774.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10635 |
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| Residue: | 497 |
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| Sequence: | MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQ
LRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVF
LARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK
AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKV
LRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVA
DLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVI
HEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF
LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGV
FAFLVSPSPYELCAVPR
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| BDBM50295255 |
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| n/a |
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| Name | BDBM50295255 |
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| Synonyms: | 6-bromo-N-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine | CHEMBL551308 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17BrN2 |
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| Mol. Mass. | 341.245 |
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| SMILES | Brc1ccc2[nH]c3C(CCCc3c2c1)Nc1ccccc1 |
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| Structure | 
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