| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM50304794 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_606254 (CHEMBL1069944) |
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| Ki | 8.2±n/a nM |
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| Citation |  Löser, R; Gut, J; Rosenthal, PJ; Frizler, M; Gütschow, M; Andrews, KT Antimalarial activity of azadipeptide nitriles. Bioorg Med Chem Lett20:252-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM50304794 |
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| n/a |
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| Name | BDBM50304794 |
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| Synonyms: | (S)-benzyl 1-(2-cyano-1,2-dimethylhydrazinyl)-4-methyl-1-oxopentan-2-ylcarbamate | CHEMBL608115 | acs.jmedchem.1c00409_ST.401 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H24N4O3 |
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| Mol. Mass. | 332.3975 |
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| SMILES | CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N(C)N(C)C#N |r| |
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| Structure | 
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