| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50311765 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_619277 (CHEMBL1100657) |
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| Ki | 19±n/a nM |
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| Citation |  Łazewska, D; Wiecek, M; Ligneau, X; Kottke, T; Weizel, L; Seifert, R; Schunack, W; Stark, H; Kiec-Kononowicz, K Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates. Bioorg Med Chem Lett19:6682-5 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM50311765 |
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| n/a |
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| Name | BDBM50311765 |
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| Synonyms: | (R)-3-(1H-imidazol-4-yl)propyl sec-butylcarbamate | CHEMBL1080089 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H19N3O2 |
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| Mol. Mass. | 225.2875 |
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| SMILES | CC[C@@H](C)NC(=O)OCCCc1cnc[nH]1 |r| |
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| Structure | 
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