| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50315966 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_625743 (CHEMBL1104420) |
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| Ki | >10000±n/a nM |
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| Citation |  Asada, M; Obitsu, T; Kinoshita, A; Nakai, Y; Nagase, T; Sugimoto, I; Tanaka, M; Takizawa, H; Yoshikawa, K; Sato, K; Narita, M; Ohuchida, S; Nakai, H; Toda, M Discovery of novel N-acylsulfonamide analogs as potent and selective EP3 receptor antagonists. Bioorg Med Chem Lett20:2639-43 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_MOUSE | PGE receptor, EP2 subtype | Prostaglandin E2 | Prostaglandin E2 receptor EP2 subtype | Prostanoid EP2 receptor | Ptger2 | Ptgerep2 |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 40495.26 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 362 |
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| Sequence: | MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAG
SRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFF
SLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYV
QYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGS
SLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRA
LRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCG
QL
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| BDBM50315966 |
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| n/a |
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| Name | BDBM50315966 |
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| Synonyms: | 3-(4-((3-cyanophenoxy)methyl)-2-(2-(naphthalen-2-yl)ethoxy)phenyl)-N-(3,4-difluorophenylsulfonyl)propanamide | CHEMBL1092431 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H28F2N2O5S |
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| Mol. Mass. | 626.669 |
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| SMILES | Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccc(c2)C#N)cc1OCCc1ccc2ccccc2c1 |
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| Structure | 
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