Ki Summary

Reaction Details

Report a problem with these data

Target

Tumor necrosis factor receptor superfamily member 5

Ligand

BDBM50325995

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_660437 (CHEMBL1250027)

IC50

50±n/a nM

Citation

Fournel, S; Wieckowski, S; Sun, W; Trouche, N; Dumortier, H; Bianco, A; Chaloin, O; Habib, M; Peter, JC; Schneider, P; Vray, B; Toes, RE; Offringa, R; Melief, CJ; Hoebeke, J; Guichard, G C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L. Nat Chem Biol1:377-82 (2005) [PubMed]

More Info.:

Get all data from this article, Assay Method

Tumor necrosis factor receptor superfamily member 5

Name:

Tumor necrosis factor receptor superfamily member 5

Synonyms:

Type:

PROTEIN

Mol. Mass.:

30614.16

Organism:

Homo sapiens (Human)

Description:

ChEMBL_660437

Residue:

277

Sequence:

MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECL
PCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCV
LHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTN
KTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVAKKPTNKAPHPKQEPQEINFPD
DLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ

BDBM50325995

n/a

Name

BDBM50325995

Synonyms:

(2S,2'S,2''S)-N,N',N''-((4S,4'S,4''S,7S,7'S,7''S)-20,20',20''-((2S,5S,10S)-7,12-dioxo-1,4,8-triazacyclododecane-2,5,10-triyl)tris(4,7-bis(4-hydroxybenzyl)-2,5,8,15-tetraoxo-3'',6'',9'',16''-tetraazaicosane-20,1-diyl))tris(2,6-diaminohexanamide) | CHEMBL1241018

Type

Small organic molecule

Emp. Form.

C117H176N24O23

Mol. Mass.

2286.7963

SMILES

NCCCC[C@H](N)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCCCC(=O)NCCCC[C@@H]1CNC(=O)C[C@H](CCCCNC(=O)CCCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)[C@@H](N)CCCCN)NC[C@H](CCCCNC(=O)CCCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)[C@@H](N)CCCCN)NC(=O)C1 |r|

Structure