| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H2 receptor |
|---|
| Ligand | BDBM50334457 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_700873 (CHEMBL1646432) |
|---|
| Ki | 2148±n/a nM |
|---|
| Citation |  Banister, SD; Moussa, IA; Beinat, C; Reynolds, AJ; Schiavini, P; Jorgensen, WT; Kassiou, M Trishomocubane as a scaffold for the development of selective dopamine transporter (DAT) ligands. Bioorg Med Chem Lett21:38-41 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H2 receptor |
|---|
| Name: | Histamine H2 receptor |
|---|
| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40115.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 359 |
|---|
| Sequence: | MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSL
AITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVM
GAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQ
QLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
|
|
|
|---|
| BDBM50334457 |
|---|
| n/a |
|---|
| Name | BDBM50334457 |
|---|
| Synonyms: | CHEMBL1643899 | N-(3-Fluorobenzyl)-8-aminopentacyclo[5.4.0.02,6.03,10.05,9]undecane |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20FN |
|---|
| Mol. Mass. | 269.3565 |
|---|
| SMILES | Fc1cccc(CN[C@@H]2C3C4CC5C6CC(C3C46)C25)c1 |r,THB:9:16:14:12.18,8:18:16.17:14,10:17:14:12.18,11:12:16.17:14| |
|---|
| Structure | 
|
|---|
Search and Browse
