| Reaction Details |
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 | Report a problem with these data |
| Target | Interstitial collagenase |
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| Ligand | BDBM50335495 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_702131 (CHEMBL1655468) |
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| Ki | 140000±n/a nM |
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| Citation |  Testero, SA; Lee, M; Staran, RT; Espahbodi, M; Llarrull, LI; Toth, M; Mobashery, S Sulfonate-Containing Thiiranes as Selective Gelatinase Inhibitors ACS Med Chem Lett2:177-181 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Interstitial collagenase |
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| Name: | Interstitial collagenase |
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| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54010.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P03956 |
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| Residue: | 469 |
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| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
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| BDBM50335495 |
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| n/a |
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| Name | BDBM50335495 |
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| Synonyms: | 4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl methanesulfonate | CHEMBL1651842 | US10357546, JNMS-38 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16O6S3 |
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| Mol. Mass. | 400.49 |
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| SMILES | CS(=O)(=O)Oc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1 |
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| Structure | 
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