| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM50335923 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_717466 (CHEMBL1670671) |
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| Ki | 480±n/a nM |
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| Citation |  Naik, P; Murumkar, P; Giridhar, R; Yadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem18:8418-56 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41201.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Angiotensin II, central 0 0::P50052 |
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| Residue: | 363 |
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| Sequence: | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
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|
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| BDBM50335923 |
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| n/a |
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| Name | BDBM50335923 |
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| Synonyms: | 1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-2,2-difluoro-2-(2-propyl-1H-benzo[d]imidazol-1-yl)ethanol | CHEMBL1668003 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22F2N6O |
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| Mol. Mass. | 460.4786 |
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| SMILES | CCCc1nc2ccccc2n1C(F)(F)C(O)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1 |
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| Structure | 
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