| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50282383 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_717439 (CHEMBL1670338) |
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| IC50 | 0.7±n/a nM |
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| Citation |  Naik, P; Murumkar, P; Giridhar, R; Yadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem18:8418-56 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41009.15 |
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| Organism: | RABBIT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RABBIT::P34976 |
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| Residue: | 359 |
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| Sequence: | MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
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| BDBM50282383 |
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| n/a |
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| Name | BDBM50282383 |
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| Synonyms: | 2-Ethyl-5,7-dimethyl-3-[2'-(2-oxo-2,3-dihydro-2lambda*4*-[1,2,3,5]oxathiadiazol-4-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine | CHEMBL344407 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23N5O2S |
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| Mol. Mass. | 445.537 |
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| SMILES | CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1C1=NS(=O)ON1 |t:30| |
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| Structure | 
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