| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50029659 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_717480 (CHEMBL1670685) |
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| IC50 | 370±n/a nM |
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| Citation |  Naik, P; Murumkar, P; Giridhar, R; Yadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem18:8418-56 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_CAVPO | AT1 | Angiotensin II type-1 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41004.19 |
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| Organism: | Cavia porcellus |
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| Description: | ChEMBL_36783 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE
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| BDBM50029659 |
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| n/a |
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| Name | BDBM50029659 |
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| Synonyms: | 2-Methyl-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylsulfanyl]-quinoline | CHEMBL142860 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H17N5S |
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| Mol. Mass. | 395.48 |
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| SMILES | Cc1cc(Sc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2ccccc2n1 |
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| Structure | 
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