Reaction Details | |||
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Target | Dipeptidyl peptidase 4 | ||
Ligand | BDBM50338456 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_728292 (CHEMBL1687449) | ||
IC50 | 110±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Dipeptidyl peptidase 4 | |||
Name: | Dipeptidyl peptidase 4 | ||
Synonyms: | ADABP | ADCP2 | Adenosine deaminase complexing protein 2 | CD26 | CD_antigen=CD26 | DPP IV | DPP4 | DPP4_HUMAN | DPPIV | Dipeptidyl peptidase 4 (DDP-IV) | Dipeptidyl peptidase 4 (DPP IV) | Dipeptidyl peptidase 4 (DPP-4) | Dipeptidyl peptidase 4 (DPP4) | Dipeptidyl peptidase 4 (DPPIV) | Dipeptidyl peptidase 4 membrane form | Dipeptidyl peptidase 4 soluble form | Dipeptidyl peptidase IV | Dipeptidyl peptidase IV (DDP-4) | Dipeptidyl peptidase IV (DDP-IV) | Dipeptidyl peptidase IV (DPP IV) | Dipeptidyl peptidase IV membrane form | Dipeptidyl peptidase IV soluble form | Dipeptidyl peptidase-IV (DPP-4) | Dipeptidyl peptidase-IV (DPP-IV) | T-cell activation antigen CD26 | TP103 | ||
Type: | Enzyme | ||
Mol. Mass.: | 88271.01 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P27487 | ||
Residue: | 766 | ||
Sequence: |
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BDBM50338456 | |||
n/a | |||
Name | BDBM50338456 | ||
Synonyms: | CHEMBL1683090 | trans-N-(4-((R)-1-amino-2-(2,5-difluorophenyl)ethyl)cyclohexyl)-N-methylpyridine-3-sulfonamide | ||
Type | Small organic molecule | ||
Emp. Form. | C20H25F2N3O2S | ||
Mol. Mass. | 409.493 | ||
SMILES | CN([C@H]1CC[C@@H](CC1)[C@H](N)Cc1cc(F)ccc1F)S(=O)(=O)c1cccnc1 |r,wU:8.9,2.1,wD:5.5,(.5,-42.99,;.5,-41.45,;-.83,-40.68,;-2.17,-41.45,;-3.49,-40.68,;-3.49,-39.14,;-2.16,-38.36,;-.83,-39.14,;-4.82,-38.37,;-4.83,-36.83,;-6.16,-39.15,;-7.49,-38.38,;-7.5,-36.83,;-8.83,-36.06,;-8.84,-34.52,;-10.16,-36.84,;-10.16,-38.38,;-8.83,-39.15,;-8.83,-40.69,;1.84,-40.69,;1.06,-39.35,;2.6,-39.35,;3.17,-41.46,;4.49,-40.69,;5.81,-41.45,;5.82,-42.99,;4.49,-43.76,;3.16,-42.99,)| | ||
Structure | ![]() |