| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-galactosidase |
|---|
| Ligand | BDBM50341334 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_742453 (CHEMBL1769101) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Díaz, L; Casas, J; Bujons, J; Llebaria, A; Delgado, A New glucocerebrosidase inhibitors by exploration of chemical diversity of N-substituted aminocyclitols using click chemistry and in situ screening. J Med Chem54:2069-79 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-galactosidase |
|---|
| Name: | Beta-galactosidase |
|---|
| Synonyms: | β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 73420.88 |
|---|
| Organism: | Bos taurus (Bovine) |
|---|
| Description: | n/a |
|---|
| Residue: | 653 |
|---|
| Sequence: | MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVP
RFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILR
PGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPII
TVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVD
FSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGA
NVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVP
EGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTM
LPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMG
RVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAH
SPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTL
FVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
|
|
|
|---|
| BDBM50341334 |
|---|
| n/a |
|---|
| Name | BDBM50341334 |
|---|
| Synonyms: | CHEMBL1766473 | rel-(1R,2S,4R,5S)-6-[(1-Adamantyl-1H-1,2,3-triazol-4-yl)methylamino]cyclohexane-1,2,3,4,5-pentaol |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H32N4O5 |
|---|
| Mol. Mass. | 408.4919 |
|---|
| SMILES | O[C@H]1[C@H](O)[C@@H](O)[C@H](NCc2cn(CC34CC5CC(CC(C5)C3)C4)nn2)[C@@H](O)[C@@H]1O |r,TLB:12:13:16:20.19.18,THB:14:15:18:22.13.21,14:13:16.15.20:18,21:13:16:20.19.18,21:19:16:22.14.13,12:13:16.15.20:18| |
|---|
| Structure | 
|
|---|
Search and Browse
